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The World Health Organisation has authorized the first malaria vaccine for widespread use in Africa.

For WHO Director, Tedros Adhanom, it was a significant moment in history.

Malaria is a disease transmitted by mosquitoes, which kills more than 400,000 people a year, mostly children in Africa.

The decision to approve the vaccine was taken after a test programme in Ghana, Kenya and Malawi proved successful.

WHO Africa's director Matshidiso Moeti comments.

The vaccine produced by GlaxoSmithKline was first developed in 1987 and it has taken over 30 years to reach the point of rollout.

It's now recommended for children in sub-Saharan Africa and other regions with moderate to high malaria transmission.

More than half of malaria deaths are in sub-Saharan African countries with one child dying every two minutes.

Pamela Amboko is a nurse, administering the vaccine at a centre in Kenya.

The vaccine acts against the deadliest malaria parasites.

Each child will need to receive four doses before the age of two for it to be most effective.

As further vaccines are in development by BioNtech and Britain's Oxford University, the challenge remains as to how to finance their effective deployment, but with the estimated cost of malaria to the African economy, of around $12 billion a year, a solution is urgently needed.

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