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The World Health Organisation has approved the use of Africa's first vaccine for malaria.
Director Tedros Adhanom said it was a historic day.
Annually, over 400,000 people, most of whom are children in Africa, die of malaria.
The disease is passed on by mosquitoes.
Before approving its use throughout the continent, the vaccine was successfully tested in Ghana, Kenya and Malawi.
Matshidiso Moeti is WHO Africa's director.
GlaxoSmithKline developed the vaccine in 1987.
However, it has taken more than 30 years for it to now be widely available.
Children in regions with above average levels of malaria will be offered the vaccine.
More than half of malaria deaths are in sub- Saharan African countries, where one child dies every two minutes.
Pamela Amboko is a nurse at a centre in Kenya.
For it to work as well as possible, children must receive four doses of the vaccine by two years old.
More new vaccines are being developed by BioNtech and Oxford University.
Although vaccines are costly to develop and distribute, the cost of malaria is even higher.
Estimates suggest that malaria costs Africa 12 billion dollars a year, so there is an urgent need for these vaccines across the continent.
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